Detalhe da pesquisa
1.
Pheophorbide A: Fluorescent Bcrp Substrate to Measure Oral Drug-Drug Interactions in Real-Time In Vivo.
Drug Metab Dispos
; 46(11): 1725-1733, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30111622
2.
Ketamine Pharmacokinetics and Pharmacodynamics Are Altered by P-Glycoprotein and Breast Cancer Resistance Protein Efflux Transporters in Mice.
Drug Metab Dispos
; 46(7): 1014-1022, 2018 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29674491
3.
In Vivo Imaging of Human MDR1 Transcription in the Brain and Spine of MDR1-Luciferase Reporter Mice.
Drug Metab Dispos
; 43(11): 1646-54, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-26281846
4.
Thiazolopyridone ureas as DNA gyrase B inhibitors: optimization of antitubercular activity and efficacy.
Bioorg Med Chem Lett
; 24(3): 870-9, 2014 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24405701
5.
Subcutaneous Administration of Monoclonal Antibodies: Pharmacology, Delivery, Immunogenicity, and Learnings From Applications to Clinical Development.
Clin Pharmacol Ther
; 115(3): 422-439, 2024 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-38093583
6.
In vitro and in vivo efficacy of ß-lactams against replicating and slowly growing/nonreplicating Mycobacterium tuberculosis.
Antimicrob Agents Chemother
; 57(6): 2506-10, 2013 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-23507276
7.
Monoclonal antibodies against GFRα3 are efficacious against evoked hyperalgesic and allodynic responses in mouse join pain models but, one of these, REGN5069, was not effective against pain in a randomized, placebo-controlled clinical trial in patients with osteoarthritis pain.
Neurobiol Pain
; 14: 100136, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-38099276
8.
Effect of coadministration of moxifloxacin and rifampin on Mycobacterium tuberculosis in a murine aerosol infection model.
Antimicrob Agents Chemother
; 56(6): 3054-7, 2012 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-22470118
9.
External Evaluation of Risperidone Population Pharmacokinetic Models Using Opportunistic Pediatric Data.
Front Pharmacol
; 13: 817276, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35370711
10.
Development and Evaluation of a Virtual Population of Children with Obesity for Physiologically Based Pharmacokinetic Modeling.
Clin Pharmacokinet
; 61(2): 307-320, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34617262
11.
Repeat subcutaneous administration of casirivimab and imdevimab in adults is well-tolerated and prevents the occurrence of COVID-19.
Int J Infect Dis
; 122: 585-592, 2022 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-35788416
12.
Physiologically Based Pharmacokinetic Modeling of Meropenem in Preterm and Term Infants.
Clin Pharmacokinet
; 60(12): 1591-1604, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34155614
13.
Metabolomic and transcriptomic analysis reveals endogenous substrates and metabolic adaptation in rats lacking Abcg2 and Abcb1a transporters.
PLoS One
; 16(7): e0253852, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34255797
14.
REGEN-COV® antibody cocktail bioanalytical strategy: comparison of LC-MRM-MS and immunoassay methods for drug quantification.
Bioanalysis
; 13(24): 1827-1836, 2021 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-34743612
15.
Role of Vitamins A and D in BCR-ABL Arf-/- Acute Lymphoblastic Leukemia.
Sci Rep
; 10(1): 2359, 2020 02 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32047189
16.
Novel N-linked aminopiperidine-based gyrase inhibitors with improved hERG and in vivo efficacy against Mycobacterium tuberculosis.
J Med Chem
; 57(11): 4889-905, 2014 Jun 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-24809953
17.
Effect of repeated dosing on rifampin exposure in BALB/c mice.
Eur J Pharm Sci
; 49(1): 33-8, 2013 Apr 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-23395915
18.
Thiazolopyridine ureas as novel antitubercular agents acting through inhibition of DNA Gyrase B.
J Med Chem
; 56(21): 8834-48, 2013 Nov 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-24088190